Germ cell tumours of the testis

摘要: Abstract Cancer of the testis is a relatively rare disease, accounting for about 1% all cancers in men. Cryptorchidism only confirmed risk factor testicular germ cell tumour. The majority GCT are clinically detectable at initial presentation. Any nodular, hard, or fixed area discovered testis, must be considered neoplastic until proved otherwise. appropriate surgical procedure to make diagnosis radical orchidectomy through an inguinal incision. Many produce tumoural markers (AFP, HCG, LDH), who useful and staging disease; monitor therapeutic response detect tumour recurrence. In 1997 prognostic factor-based classification metastatic tumours was developed by IGCCCG: good, intermediate poor prognosis, with 5-year survival 91, 79 48%, respectively. highly table, often curable, cancer. Germ divided into seminoma non-seminoma types treatment planning because seminomatous more sensitive radiotherapy. Seminoma (all stages combined) has cure rate greater than 90%. For patients low-stage approaches 100%. tumours, >95% I II; it ∼70% standard chemotherapy resection residual if necessary, III IV. Minimum guidelines clinical, biochemical, radiological follow-up have been reported ESMO 2001.