Parkinson's Disease: Symptoms and Age Dependency

摘要: Parkinson's disease is a major neurodegenerative mainly affecting the elders. In autopsy studies, diagnosis of before death found to be incorrect in number cases. contrast, may misdiagnosed as depression, or very elderly, “normal” aging. Other disorders, like progressive nuclear palsy multiple system atrophy, not distinguished easily from early course disease. This chapter also discusses classic triad symptoms disease, which consists tremor, rigidity, and hypokinesia. stages signs vague nonspecific such way that trustworthy cannot yet made. Symptoms can gravitated by contralateral activation, concentration on mental physical tasks. The stresses fact gait impaired patients with Although most important lesion located substantia nigra its dopaminergic projections, lesions presynaptic nigrostriatal dopamine lead widespread abnormalities regional brain metabolism.