Examination of Physiological Function and Biochemical Disorders in a Rat Model of Prolonged Asphyxia-Induced Cardiac Arrest followed by Cardio Pulmonary Bypass Resuscitation
作者： Junhwan Kim , Tai Yin , Ming Yin , Wei Zhang , Koichiro Shinozaki
DOI: 10.1371/JOURNAL.PONE.0112012
关键词:
摘要: Background Cardiac arrest induces whole body ischemia, which causes damage to multiple organs particularly the heart and brain. There is clinical preclinical evidence that neurological injury responsible for high mortality morbidity of patients even after successful cardiopulmonary resuscitation. A better understanding metabolic alterations in brain during ischemia will enable development targeted resuscitation protocols repair ischemic minimize additional caused by reperfusion.
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