Influenza AH1N2 Viruses, United Kingdom, 2001–02 Influenza Season

作者: Joanna S. Ellis , Adriana Alvarez-Aguero , Vicky Gregory , Yi Pu Lin , A. Hay

DOI: 10.3201/EID0903.020404

关键词:

摘要: During the winter of 2001–02, influenza AH1N2 viruses were detected for first time in humans U.K. The H1N2 co-circulated with H3N2 and a very small number H1N1 isolated community hospitalized patients, predominantly from children <15 years age. Characterization indicated that they antigenically genetically homogeneous, deriving hemagglutinin (HA) gene recently circulating A/New Caledonia/20/99-like viruses, whereas other seven genes originated viruses. Retrospective reverse transcription-polymerase chain reaction analysis A H1 during previous identified single virus, March 2001, indicating did not widely circulate before September 2001. reassortment event is estimated to have occurred between 1999 early emergence reinforces need frequent surveillance

参考文章(37)
N. J. Cox, A. P. Kendal, Z. S. Bai, Laboratory-based surveillance of influenza A(H1N1) and A(H3N2) viruses in 1980-81: antigenic and genomic analyses Bulletin of The World Health Organization. ,vol. 61, pp. 143- 152 ,(1983)
D Fleming, N L Goddard, M Nunn, C A Joseph, J M Watson, M Zambon, Influenza surveillance in England and Wales: October 1999 to May 2000. Communicable disease and public health. ,vol. 3, pp. 261- 266 ,(2000)
Y Kawaoka, S Krauss, R G Webster, Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics. Journal of Virology. ,vol. 63, pp. 4603- 4608 ,(1989) , 10.1128/JVI.63.11.4603-4608.1989
Alexander I. Karasin, Gary A. Anderson, Christopher W. Olsen, Genetic Characterization of an H1N2 Influenza Virus Isolated from a Pig In Indiana Journal of Clinical Microbiology. ,vol. 38, pp. 2453- 2456 ,(2000) , 10.1128/JCM.38.6.2453-2456.2000
M. J. Espy, P. N. Rys, A. D. Wold, J. R. Uhl, L. M. Sloan, G. D. Jenkins, D. M. Ilstrup, F. R. Cockerill, R. Patel, J. E. Rosenblatt, T. F. Smith, Detection of Herpes Simplex Virus DNA in Genital and Dermal Specimens by LightCycler PCR after Extraction using the IsoQuick, MagNA Pure, and BioRobot 9604 Methods Journal of Clinical Microbiology. ,vol. 39, pp. 2233- 2236 ,(2001) , 10.1128/JCM.39.6.2233-2236.2001
Xu Xiyan, Elisabet P. Rocha, Helen L. Regenery, Alan P. Kendal, Nancy J. Cox, Genetic and antigenic analyses of influenza A (H1N1) viruses, 1986-1991 Virus Research. ,vol. 28, pp. 37- 55 ,(1993) , 10.1016/0168-1702(93)90088-5
V. Gregory, M. Bennett, M.H. Orkhan, S. Al Hajjar, N. Varsano, E. Mendelson, M. Zambon, J. Ellis, A. Hay, Y.P. Lin, Emergence of Influenza A H1N2 Reassortant Viruses in the Human Population during 2001 Virology. ,vol. 300, pp. 1- 7 ,(2002) , 10.1006/VIRO.2002.1513
Dirk B. Mendel, Robert W. Sidwell, Influenza virus resistance to neuraminidase inhibitors Drug Resistance Updates. ,vol. 1, pp. 184- 189 ,(1998) , 10.1016/S1368-7646(98)80038-1