Drugs for BNCT: BSH and BPA

作者: Wolfgang A. G. Sauerwein , Pierre M. Bet , Andrea Wittig

DOI: 10.1007/978-3-642-31334-9_8

关键词:

摘要: This chapter is based on a shortened version of the investigators brochures from EORTC clinical trials 11001 and 11011 concerning boron compounds sodium borocaptate (BSH) boronophenylalanine (BPA). It summarizes essential information that might be asked by regulatory authorities. The intention this to support facilitate preparation new these compounds. However, compilation cannot offer complete final description all aspects 2 necessary file for drug approval.

参考文章(119)
F. Basilico, W. Sauerwein, F. Pozzi, A. Wittig, R. Moss, P. L. Mauri, Analysis of 10B antitumoral compounds by means of flow-injection into ESI-MS/MS Journal of Mass Spectrometry. ,vol. 40, pp. 1546- 1549 ,(2005) , 10.1002/JMS.909
G. M. Morris, G. Constantine, G. Ross, T. K. Yeung, J. W. Hopewell, Boron neutron capture therapy: long-term effects on the skin and spinal cord of the rat Radiation Research. ,vol. 135, pp. 380- 386 ,(1993) , 10.2307/3578878
Mario A Pisarev, Maria A Dagrosa, Guillermo J Juvenal, Application of boron neutron capture therapy to the treatment of anaplastic thyroid carcinoma: current status and future perspectives Current Opinion in Endocrinology & Diabetes. ,vol. 12, pp. 352- 355 ,(2005) , 10.1097/01.MED.0000178269.16988.B1
Shinji Kawabata, Shin-Ichi Miyatake, Naosuke Nonoguchi, Ry. Hiramatsu, Kyoko Iida, Shiro Miyata, Kunio Yokoyama, Atsushi Doi, Yuzo Kuroda, Toshihiko Kuroiwa, Hiroyuki Michiue, Hiroaki Kumada, Mitsunori Kirihata, Yoshio Imahori, Akira Maruhashi, Yoshinori Sakurai, Minoru Suzuki, Shin-Ichiro Masunaga, Koji Ono, Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients. Applied Radiation and Isotopes. ,vol. 67, ,(2009) , 10.1016/J.APRADISO.2009.03.015
Sven Harfst, Detlef Moller, Hartmut Ketz, Jens Rösler, Detlef Gabel, Reversed-phase separation of ionic organoborate clusters by high-performance liquid chromatography Journal of Chromatography A. ,vol. 678, pp. 41- 48 ,(1994) , 10.1016/0021-9673(94)87072-1
Dietrich Haritz, Detlef Gabel, René Huiskamp, Clinical phase-I study of Na2B12H11SH (BSH) in patients with malignant glioma as precondition for boron neutron capture therapy (BNCT) International Journal of Radiation Oncology Biology Physics. ,vol. 28, pp. 1175- 1181 ,(1994) , 10.1016/0360-3016(94)90492-8
NORIKAZU TAMAOKI, MASATO UEDA, SHUICHI TAMAUCHI, KUMIKO YAMAMOTO, YUTAKA MISHIMA, Use of nude mice in experimental neutron capture therapy with 10B-BPA. Pigment Cell Research. ,vol. 2, pp. 343- 344 ,(1989) , 10.1111/J.1600-0749.1989.TB00216.X
I JANKU, E BUCHAR, Z JIRICKA, Nephrotoxicity of borocaptate after short-term administration in rabbits. Toxicology. ,vol. 79, pp. 99- 108 ,(1993) , 10.1016/0300-483X(93)90123-A
S. Altieri, S. Bortolussi, P. Bruschi, P. Chiari, F. Fossati, S. Stella, U. Prati, L. Roveda, A. Zonta, C. Zonta, C. Ferrari, A. Clerici, R. Nano, T. Pinelli, Neutron autoradiography imaging of selective boron uptake in human metastatic tumours Applied Radiation and Isotopes. ,vol. 66, pp. 1850- 1855 ,(2008) , 10.1016/J.APRADISO.2008.05.007