GERMINAL-CENTERS AND THE B-CELL SYSTEM .3. GERMINAL CENTER FORMING CAPACITY OF RABBIT APPENDIX GERMINAL CENTER (-DERIVED) CELLS
作者： Dieuwertje Heijden , O. Nieweg , B. Rijkmans , Rita Stikker , Davine Opstelten
DOI: 10.1007/BF02892406
关键词:
摘要: Functional capacities of rabbit appendix germinal centre cells were tested in appendectomized, 450 rads X-irradiated rabbits, reconstituted with autologous cells, which are obtained by mechanical separation - “stripping” the appendix. For comparison, functional derived shielded. In both types experimental systems, slow restoration primary IgM responsiveness to Salmonella Java paratyphi-B (PAR) was observed ; contrast, capacity for memory cell production (of μ and γ-type) PAR restored very early systems. These results suggest centres be antigen dependent microenvironments selective as well non-selective amplification ofimmature B after subsequent maturation become part pool either or virgin mature respectively.
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[No Value] Nieuwenh.P, Fj Keuning, GERMINAL CENTERS AND ORIGIN OF B-CELL SYSTEM .2. GERMINAL CENTERS IN RABBIT SPLEEN AND POPLITEAL LYMPH-NODES Immunology. ,vol. 26, pp. 509- 519 ,(1974)
[No Value] Nieuwenh.P, Jh Eggens, Fj Keuning, [No Value] Vannouhu.Ce, GERMINAL CENTERS AND ORIGIN OF B-CELL SYSTEM .1. GERMINAL CENTERS IN RABBIT APPENDIX Immunology. ,vol. 26, pp. 497- 507 ,(1974)
H. Ozer, B.H. Waksman, Appendix and γM-antibody formation: VII. Rosette-forming cells in rabbits immunized with sheep erythrocytes☆ Cellular Immunology. ,vol. 24, pp. 355- 364 ,(1976) , 10.1016/0008-8749(76)90219-7
B. H. Waksman, H. Ozer, Appendix and M antibody formation. V. Appendix and thymus cell synergism in the direct and indirect plaque-forming cell responses to sheep erythrocytes in the rabbit. Journal of Immunology. ,vol. 109, pp. 410- 412 ,(1972)
J. Baker, M. C. Howard, J. M. Fidler, K. Shortman, Antigen-initiated b lymphocyte differentiation. Xiii. Different b cell subsets give different afc-production kinetics and respond in different functional assays. Journal of Immunology. ,vol. 122, pp. 309- 319 ,(1979)
R. M. E. Parkhouse, Erika R. Abney, John F. Kearney, Max D. Cooper, Alexander R. Lawton, Sequential Expression of Immunoglobulin on Developing Mouse B Lymphocytes: A Systematic Survey That Suggests a Model for the Generation of Immunoglobulin Isotype Diversity Journal of Immunology. ,vol. 120, pp. 2041- 2049 ,(1978)
G G Klaus, The generation of memory cells. II. Generation of B memory cells with preformed antigen-antibody complexes. Immunology. ,vol. 34, pp. 643- ,(1978)
Joan M. Carboni, Byron H. Waksman, Catherine E. Calkins, B Cells in the Appendix and Other Lymphoid Organs of the Rabbit: Complement Receptor Lymphocytes Journal of Immunology. ,vol. 115, pp. 1339- 1345 ,(1975)
Byron H. Waksman, K. Nomoto, M. Hanaoka, APPENDIX AND $gamma$M-ANTIBODY FORMATION. I. IMMUNE RESPONSE AND TOLERANCE TO BOVINE $gamma$ GLOBULIN IN IRRADIATED, APPENDIX-SHIELDED RABBITS. Journal of Immunology. ,vol. 104, pp. 616- 625 ,(1970)
T Yokochi, F Nagase, N Kato, I Nakashima, Competition of the actions of antigen and polyclonal b-cell activator in the induction and amplification of b-memory cell function. Immunology. ,vol. 35, pp. 511- 518 ,(1978)