Chemoembolization of rat liver metastasis with irinotecan and quantification of tumor cell reduction

作者: Jan Saenger , Maike Leible , Matthias H. Seelig , Martin R. Berger

DOI: 10.1007/S00432-003-0523-X

关键词:

摘要: Purpose Hematogenic metastasis of patients with colorectal cancer most frequently effects the liver; prognosis affected is dramatically worsened by presence this lesion. The aim study was to evaluate effect hepatic arterial chemoembolization (HACE) irinotecan versus 5-fluorouracil as a standard agent in rat liver model.

参考文章(44)
Axel Wittmer, Khashayarsha Khazaie, Martin R. Berger, Quantitative detection of lac-Z-transfected CC531 colon carcinoma cells in an orthotopic rat liver metastasis model. Clinical & Experimental Metastasis. ,vol. 17, pp. 369- 376 ,(1999) , 10.1023/A:1006643831825
Martin Hagenaars, Ron Koelemij, N. Geeske Ensink, Jaap D.H. van Eendenburg, Ronald L.P. van Vlierberghe, Alexander M.M. Eggermont, Cornelis J.H. van de Velde, Gert Jan Fleuren, Peter J.K. Kuppen, The development of novel mouse monoclonal antibodies against the CC531 rat colon adenocarcinoma Clinical & Experimental Metastasis. ,vol. 18, pp. 281- 289 ,(2000) , 10.1023/A:1011062002851
H C Pitot, D B Wender, M J O'Connell, G Schroeder, R M Goldberg, J Rubin, J A Mailliard, J A Knost, C Ghosh, R J Kirschling, R Levitt, H E Windschitl, Phase II Trial of Irinotecan in Patients With Metastatic Colorectal Carcinoma Journal of Clinical Oncology. ,vol. 15, pp. 2910- 2919 ,(1997) , 10.1200/JCO.1997.15.8.2910
Lian-Xin Liu, Wei-Hui Zhang, Hong-Chi Jiang, Current treatment for liver metastases from colorectal cancer World Journal of Gastroenterology. ,vol. 9, pp. 193- 200 ,(2003) , 10.3748/WJG.V9.I2.193
Bengt Glimelius, Wilhelm Graf, Håkan Ahlström, Anders Magnusson, Anders Sundín, Contrast-enhanced CT scanning in vivo for the quantification of hepatic metastases from a human colonic cancer in the nude rat. Ejso. ,vol. 18, pp. 615- 623 ,(1992)
J. G. Geoghegan, J. Scheele, Treatment of colorectal liver metastases. British Journal of Surgery. ,vol. 86, pp. 158- 169 ,(2003) , 10.1046/J.1365-2168.1999.01013.X
Y H Hsiang, R Hertzberg, S Hecht, L F Liu, Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. Journal of Biological Chemistry. ,vol. 260, pp. 14873- 14878 ,(1985) , 10.1016/S0021-9258(17)38654-4
P Rougier, A Laplanche, M Huguier, J M Hay, J M Ollivier, J Escat, R Salmon, M Julien, J C Roullet Audy, D Gallot, Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial. Journal of Clinical Oncology. ,vol. 10, pp. 1112- 1118 ,(1992) , 10.1200/JCO.1992.10.7.1112
M L Rothenberg, J R Eckardt, J G Kuhn, H A Burris, J Nelson, S G Hilsenbeck, G I Rodriguez, A M Thurman, L S Smith, S G Eckhardt, G R Weiss, G L Elfring, D A Rinaldi, L J Schaaf, D D Von Hoff, Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. Journal of Clinical Oncology. ,vol. 14, pp. 1128- 1135 ,(1996) , 10.1200/JCO.1996.14.4.1128
William D. Ensminger, Susan J. DeRemer, Philip L. Stetson, James A. Knol, Zhaomin Yang, David E. Smith, Han Yi Kuan, Regional Pharmacokinetics of 5-Bromo-2′-deoxyuridine and 5-Fluorouracil in Dogs: Hepatic Arterial versus Portal Venous Infusions Cancer Research. ,vol. 56, pp. 4724- 4727 ,(1996)