Signaling pathways during maintenance and definitive endoderm differentiation of embryonic stem cells
作者： Lina Sui , Luc Bouwens , Josué K. Mfopou
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摘要: Embryonic stem cells (ESCs) have the potential to be used as unlimited resources for tissue replacement therapy, thereby compensating organ donor shortage. To reach this goal, molecular principles governing early differentiation events in developing embryo need addressed, understood and properly implemented vitro. Studies carried out several vertebrate models established that Nodal/Activin A, BMP, WNT FGF signaling pathways regulate development these are similarly during germ layer formation by cultured ESCs. However, differences also been identified way function or interact mouse vs. human ESCs, making it sometimes difficult extrapolate findings from one system other. In review, we discuss compare role of relevant their crosstalk undifferentiated growth endoderm
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Adam Rodaway, Roger Patient, Mesendoderm. an ancient germ layer Cell. ,vol. 105, pp. 169- 172 ,(2001) , 10.1016/S0092-8674(01)00307-5
Bernard Thisse, Christopher V. E. Wright, Christine Thisse, Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature. ,vol. 403, pp. 425- 428 ,(2000) , 10.1038/35000200
Pentao Liu, Maki Wakamiya, Martin J. Shea, Urs Albrecht, Richard R. Behringer, Allan Bradley, Requirement for Wnt3 in vertebrate axis formation Nature Genetics. ,vol. 22, pp. 361- 365 ,(1999) , 10.1038/11932
Christine Mummery, Marcel A. G. van der Heyden, Teun P. de Boer, Robert Passier, Dorien Ward, Stieneke van den Brink, Marga van Rooijen, Anja van de Stolpe, Cardiomyocytes From Human and Mouse Embryonic Stem Cells Methods in molecular medicine. ,vol. 140, pp. 249- 272 ,(2007) , 10.1007/978-1-59745-443-8_14
A. Rodaway, H. Takeda, N. Holder, B. Price, J. Broadbent, R. Patient, J.C. Smith, S. Koshida, Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-beta family signals and discrimination of mesoderm and endoderm by FGF. Development. ,vol. 126, pp. 3067- 3078 ,(1999) , 10.1242/DEV.126.14.3067
J.J. Meneses, R.A. Pedersen, K.A. Lawson, Clonal analysis of epiblast fate during germ layer formation in the mouse embryo Development. ,vol. 113, pp. 891- 911 ,(1991) , 10.1242/DEV.113.3.891
E.J. Robertson, R.S. Beddington, An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo. Development. ,vol. 105, pp. 733- 737 ,(1989) , 10.1242/DEV.105.4.733
Masahiro Yasunaga, Shinsuke Tada, Satomi Torikai-Nishikawa, Yoko Nakano, Mitsuhiro Okada, Lars Martin Jakt, Satomi Nishikawa, Tsutomu Chiba, Takumi Era, Shin-Ichi Nishikawa, Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells Nature Biotechnology. ,vol. 23, pp. 1542- 1550 ,(2005) , 10.1038/NBT1167
C. H.-H. Cho, N. R.-F. Hannan, F. M. Docherty, H. M. Docherty, M. Joåo Lima, M. W. B. Trotter, K. Docherty, L. Vallier, Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells Diabetologia. ,vol. 55, pp. 3284- 3295 ,(2012) , 10.1007/S00125-012-2687-X
Caroline R. Kemp, Erik Willems, Danuta Wawrzak, Marijke Hendrickx, Terence Agbor Agbor, Luc Leyns, Expression ofFrizzled5, Frizzled7, andFrizzled10 during early mouse development and interactions with canonical Wnt signaling Developmental Dynamics. ,vol. 236, pp. 2011- 2019 ,(2007) , 10.1002/DVDY.21198