Looking under the skin: the first steps in malarial infection and immunity

作者: Robert Ménard , Joana Tavares , Ian Cockburn , Miles Markus , Fidel Zavala

DOI: 10.1038/NRMICRO3111

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摘要: The symptoms of malaria are associated with the erythrocytic phase Plasmodium spp. infection, but pre-erythrocytic (PE) phase, which is clinically silent, has long been interest as a potential vaccination target. Robert Menard and colleagues review how our understanding PE changed over past decade this in turn informed host immune response.

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