Stay the Executioner's Hand
作者： Mark E Gurney , Alfredo G Tomasselli , Robert L Heinrikson
DOI: 10.1126/SCIENCE.288.5464.283
关键词:
摘要: ALS, also known as Lou Gehrig's disease after the American baseball star who died of illness, is characterized by death motor neurons in brain and spinal cord. In a Perspective, [Gurney colleagues][1] discuss new findings ([ Li et al .][2]) showing that mouse model survival can be prolonged administering an inhibitor caspases, enzymes act cell's executioner apoptosis. The work demonstrates die through apoptosis blocking this programmed cell with caspase might one approach to treating ALS patients. [1]: http://www.sciencemag.org/cgi/content/full/288/5464/283 [2]: http://www.sciencemag.org/cgi/content/full/288/5464/335
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