One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
作者： Hui Yang , Haoyi Wang , Chikdu S. Shivalila , Albert W. Cheng , Linyu Shi
DOI: 10.1016/J.CELL.2013.08.022
关键词:
摘要: The type II bacterial CRISPR/Cas system is a novel genome-engineering technology with the ease of multiplexed gene targeting. Here, we created reporter and conditional mutant mice …
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