Spilanthol: occurrence, extraction, chemistry and biological activities

作者: Alan F. Barbosa , Mário G. de Carvalho , Robert E. Smith , Armando U.O. Sabaa-Srur

DOI: 10.1016/J.BJP.2015.07.024

关键词:

摘要: Abstract Spilanthol (C14H23NO, 221.339 g/mol) is a bioactive compound that found in many different plants are used as traditional remedies throughout the world. It present Heliopsis longipes and several species genus Acmella, including A. oleracea L., also known paracress jambu. Its leaves flowers have sensory properties (pungency, tingling, numbing, mouth-watering) make it popular spice ingredient Brazilian dishes. can exert variety of biological pharmacological effects analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, antilarvicidal insecticidal activities. So, aim this review to literature on spilanthol describes its occurrence, chemistry, extraction

参考文章(63)
Jakob P. Ley, Gerhard Krammer, Jan Looft, Gerald Reinders, Heinz-Jürgen Bertram, Structure-activity relationships of trigeminal effects for artificial and naturally occurring alkamides related to spilanthol Developments in food science. ,vol. 43, pp. 21- 24 ,(2006) , 10.1016/S0167-4501(06)80006-3
Myrna Déciga-Campos, Myriam Arriaga-Alba, Rosa Ventura-Martínez, Berenice Aguilar-Guadarrama, María Yolanda Rios, Pharmacological and Toxicological Profile of Extract from Heliopsis longipes and Affinin Drug Development Research. ,vol. 73, pp. 130- 137 ,(2012) , 10.1002/DDR.21002
Cristina Pacheco Soares, Valeria Rosseto Lemos, Ary Gomes da Silva, Renan Meyer Campoy, Carlos Augusto Priante da Silva, Renato Farina Menegon, Iuri Rojahn, Walderez Moreira Joaquim, Effect of Spilanthes acmella hydroethanolic extract activity on tumour cell actin cytoskeleton. Cell Biology International. ,vol. 38, pp. 131- 135 ,(2014) , 10.1002/CBIN.10180
Rajnish Kumar Yadav, Siddhartha Maity, Amit Kumar Keshari, Sudipta Saha, Akanksha Mishra, Subhadeep Roy, ANTIPROLIFERATIVE EFFECT OF FLOWER EXTRACTS OF SPILANTHES PANICULATA ON HEPATIC CARCINOMA CELLS International Journal of Pharmacy and Pharmaceutical Sciences. ,vol. 7, pp. 130- 134 ,(2014)
Kevin Spelman, Delphine Depoix, Megan McCray, Elisabeth Mouray, Philippe Grellier, The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo antimalarial activity. Phytotherapy Research. ,vol. 25, pp. 1098- 1101 ,(2011) , 10.1002/PTR.3395
Nathan L. Porter, Nebojsa Avdalovic, Chris Pohl, Bruce E. Richter, Brian A. Jones, John L. Ezzell, Accelerated Solvent Extraction: A Technique for Sample Preparation Analytical Chemistry. ,vol. 68, pp. 1033- 1039 ,(1996) , 10.1021/AC9508199
Myrna Déciga-Campos, María Rios, A. Aguilar-Guadarrama, Antinociceptive effect of heliopsis longipes extract and affinin in mice Planta Medica. ,vol. 76, pp. 665- 670 ,(2010) , 10.1055/S-0029-1240658
Vibha Pandey, Madhu Chopra, Veena Agrawal, In vitro isolation and characterization of biolarvicidal compounds from micropropagated plants of Spilanthes acmella Parasitology Research. ,vol. 108, pp. 297- 304 ,(2011) , 10.1007/S00436-010-2056-Y