作者: Evagelos N. Liberopoulos , Stella S. Daskalopoulou , Dimitri P. Mikhailidis , Anthony S. Wierzbicki , Moses S. Elisaf
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摘要: ABSTRACTBackground: Statin therapy has been shown to significantly decrease vascular events and overall mortality in primary secondary prevention trials. This review considers the pharmacology, non-lipid-lowering effects clinical trial evidence of fluvastatin based on a survey PubMed entries.Findings: Recent data show that treatment with is associated variety benefits different high-risk populations along good safety profile. Fluvastatin exerts non-lipid lowering-associated pleiotropic both experimental studies. Furthermore, an extended-release formulation favourable pharmacokinetic profile available.Conclusion: Treatment offers convenient, safe evidence-based approach managing dyslipidaemias preventing events.