Phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake.

摘要: Elevated serum phosphorus has been identified as a cardiovascular risk factor in chronic kidney disease (CKD) patients and clear understanding of homeostasis is very important for practicing nephrologists. At any particular point, levels reflect the balance between movements this mineral from into intestine, bone, intracellular space, kidneys. We briefly review here all these exchanges with emphasis on dietary intake. Despite oral binders currently available market, restriction remains cornerstone prevention treatment hyperphosphatemia. An effective intake requires prescription moderate protein (0.9-1.0 g/kg/day) restricted consumption highly processed fast convenience foods. Phosphorus added during food processing an source because its magnitude high bioavailabilty. Moreover, manufacturers are not required to label amount processing, significant current daily unaccounted when estimating CKD patients. The recent development low phosphorus-containing products represents useful addition