Inhibition of natural killer cell activity in vitro by alcohols.

作者: Sandra S. Ristow , Jean R. Starkey , G.Michael Hass

DOI: 10.1016/0006-291X(82)90930-5

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摘要: Abstract The effect of the addition small quantities alcohols to cocultures natural killer effector cells from C57BL 6 mice and BDIX rats with YAC-1 tumor cell targets has been studied. order inhibition NK cell-mediated killing is 1-butanol > 1-propanol 2-propanol ethanol methanol. due alcohol correlates decreases effector-target binding. Therefore caution should be exercised in interpreting results cellular experiments which these have used solubilize inhibitors.

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