Heterozygous familial hypercholesterolaemia in childhood: cardiovascular risk prevention.
作者： A. van der Graaf , J. J. P. Kastelein , A. Wiegman
DOI: 10.1007/S10545-009-1165-1
关键词:
摘要: Children with familial hypercholesterolaemia (FH) have severely increased low-density lipoprotein cholesterol (LDL-C) levels that strongly predispose to premature cardiovascular disease (CVD) later in life. Early identification makes it possible start lipid-lowering therapy at young age prevent CVD. The atherosclerotic process can be inhibited by potent therapy. cornerstone of is a healthy lifestyle, but most the time this insufficient reach adequate LDL-C goals. Subsequently, pharmacological initiated increasing frequency. In past decade numerous studies assessed efficacy and safety statins children FH. Those demonstrate are well tolerated, safe effective. Therefore, these agents pivotal role treatment
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