The effect of L-ornithine hydrochloride ingestion on performance during incremental exhaustive ergometer bicycle exercise and ammonia metabolism during and after exercise.

作者: S Demura , T Yamada , S Yamaji , M Komatsu , K Morishita

DOI: 10.1038/EJCN.2010.149

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摘要: L-ornithine has an important role in ammonia metabolism via the urea cycle. This study aimed to examine effect of hydrochloride ingestion on performance during incremental exhaustive ergometer bicycle exercise and after exercise. In all, 14 healthy young adults (age: 22.2±1.0 years, height: 173.5±4.6 cm, body mass: 72.5±12.5 kg) who trained regularly conducted exercises -ornithine supplementation (0.1 g/kg, mass) placebo conditions with a cross-over design. The time (sec) exercise, intensity at exhaustion (watt), maximal oxygen uptake (ml per kg min), heart rate (beats min) following serum parameters were measured before ingestion, 1 h just 15 min exhaustion: ornithine, ammonia, urea, lactic acid glutamate. All indices aerobic capacity showed insignificant differences between both conditions. Plasma concentrations significantly more ornithine than placebo. glutamate higher It was suggested that, although cannot be expected improve performance, it does increase ability buffer

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