Potato plants genetically modified to produce N-acylhomoserine lactones increase susceptibility to soft rot Erwiniae.
作者： I. K. Toth , J. A. Newton , L. J. Hyman , A. K. Lees , M. Daykin
DOI: 10.1094/MPMI.2004.17.8.880
关键词:
摘要: Many gram-negative bacteria employ N-acylhomoserine lactones (AHL) to regulate diverse physiological processes in concert with cell population density (quorum sensing [QS]). In the plant pathogen Erwinia carotovora, AHL synthesized via carI/expI genes are responsible for regulating production of secreted wall-degrading exoenzymes and antibiotic carbapen-3-em carboxylic acid. We have previously shown that targeting product an synthase gene (yenI) from Yersinia enterocolitica chloroplasts transgenic tobacco plants caused synthesis planta cognate signaling molecules N-(3-oxohexanoyl)-L-homoserine lactone (3-oxo-C6-HSL) N-hexanoylhomoserine (C6-HSL), which turn, were able complement a carI-QS mutant. present study, we demonstrate potato containing yenI also express presence level these increases susceptibility infection by E. carotovora. Susceptibility is further affected both bacterial tissue under investigation.
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Rupert G. Fray, John P. Throup, Mavis Daykin, Andrew Wallace, Paul Williams, Gordon S.A.B. Stewart, Donald Grierson, Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria. Nature Biotechnology. ,vol. 17, pp. 1017- 1020 ,(1999) , 10.1038/13717
Simon Swift, J. Allan Downie, Neil A. Whitehead, Anne M.L. Barnard, George P.C. Salmond, Paul Williams, Quorum sensing as a population-density-dependent determinant of bacterial physiology. Advances in Microbial Physiology. ,vol. 45, pp. 199- 270 ,(2001) , 10.1016/S0065-2911(01)45005-3
N J Bainton, P Stead, S R Chhabra, B W Bycroft, G P C Salmond, G S A B Stewart, P Williams, N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora. Biochemical Journal. ,vol. 288, pp. 997- 1004 ,(1992) , 10.1042/BJ2880997
D. H. LAPWOOD, P. J. READ, The susceptibility of stems of different potato cultivars to blackleg caused by Erwinia carotovora subsp. atroseptica Annals of Applied Biology. ,vol. 109, pp. 555- 560 ,(1986) , 10.1111/J.1744-7348.1986.TB03212.X
Asita Mukherjee, Yaya Cui, Yang Liu, Arun K. Chatterjee, Molecular characterization and expression of the Erwinia carotovora hrpNEcc gene, which encodes an elicitor of the hypersensitive reaction Molecular Plant-microbe Interactions. ,vol. 10, pp. 462- 471 ,(1997) , 10.1094/MPMI.1997.10.4.462
Siri Ram Chhabra, Chris Harty, Doreen S. W. Hooi, Mavis Daykin, Paul Williams, Gary Telford, David I. Pritchard, Barrie W. Bycroft, Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators. Journal of Medicinal Chemistry. ,vol. 46, pp. 97- 104 ,(2003) , 10.1021/JM020909N
M. J. De Maine, A. K. Lees, J. E. Bradshaw, Soft-rot resistance combined with other tuber characters in long day-adapted Solanum phureja Potato Research. ,vol. 41, pp. 69- 82 ,(1998) , 10.1007/BF02360263
Paul Williams, Miguel Camara, Andrea Hardman, Simon Swift, Deborah Milton, Victoria J. Hope, Klaus Winzer, Barrie Middleton, David I. Pritchard, Barrie W. Bycroft, Quorum sensing and the population-dependent control of virulence Philosophical Transactions of the Royal Society B. ,vol. 355, pp. 667- 680 ,(2000) , 10.1098/RSTB.2000.0607
John Loh, Elizabeth A Pierson, Leland S Pierson, Gary Stacey, Arun Chatterjee, Quorum sensing in plant-associated bacteria. Current Opinion in Plant Biology. ,vol. 5, pp. 285- 290 ,(2002) , 10.1016/S1369-5266(02)00274-1
SIRI RAM CHHABRA, PAUL STEAD, NIGEL J. BAINTON, GEORGE P. C. SALMOND, GORDON S. A. B. STEWART, PAUL WILLIAMS, BARRIE W. BYCROFT, Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone The Journal of Antibiotics. ,vol. 46, pp. 441- 454 ,(1993) , 10.7164/ANTIBIOTICS.46.441