Expression of human β-defensin-1, -2, and -3 in non-inflamed pseudocyst, mucoceles
作者： MK Frederic , T Yamaai , N Mizukawa , Y Kaneda , N Katase
DOI: 10.1111/J.1601-0825.2008.01451.X
关键词:
摘要: Objectives and design: The expressions of human beta defensin-1 (HBD-1), -2 (HBD-2) -3 (HBD-3) in non-inflamed pseudocysts such as mucoceles were investigated immunohistochemically this study. Materials methods: Mucocele specimens obtained from 21 patients. expression HBDs was studied by using antibodies directed against HBD-1, -2, -3. Statistical analyses carried out on serial sections stained with antibodies. Results: Cells expressing found mucoceles. HBD-2 observed floating cells all the specimens, whereas HBD-1 HBD-3-expressing detected 93% 73% mucoceles, respectively. signal most intense HBD-3 intensity weaker than that HBD-1. expressed neutrophils other cells. Interestingly, population positive located close to centers cysts higher those peripheral areas cysts. Conclusion: even These results suggest an unknown mechanism not involved biophylaxis for may exist.
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