Stabilisation of Proteins
作者： Jan Jezek , Charles Potter
DOI:
关键词:
摘要: A dry composition for use in therapy or diagnosis, obtainable by drying an aqueous comprising a protein and one more displacement buffers, wherein the pH of is such that stable, each buffer has pKa at least 1 unit greater less than composition, substantially free conventional having within composition.
lens.org 参考文章(10)
Masafumi Tatsumi, Junichi Kajihara, Katsura Inoue, Human growth hormone-containing aqueous pharmaceutical composition ,(1998)
Jan Jezek, Stable Formulation of a Therapeutic Protein ,(2009)
Jorge C. De Meireles, Shyam Vangala, Malini Gupta, Steven C. Quay, Compositions and methods for enhanced mucosal delivery of growth hormone ,(2004)
Jan Jezek, Stabilization of aqueous compositions of proteins with displacement buffers ,(2008)
Jan Jezek, Stable vaccine formulation ,(2007)
Damaskus Charles W, Stabilized chymotrypsin solution ,(1957)
Jan Jezek, Stable aqueous systems comprising proteins ,(2006)
Henry Lowman, Yves Dubaquie, IGF-I variants ,(2000)
James Q. Oeswein, Barbara H. O'Connor, Human growth hormone aqueous formulation ,(1993)
Svend Havelund, Jens J. V. Brange, Stabilized insulin preparations ,(1983)