作者: Michael E. Klepser , Erika J. Ernst , Michael A. Pfaller
DOI: 10.1016/S0966-842X(97)01108-6
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摘要: Overuse of antifungal agents has resulted in the selection naturally resistant Candida species, as well expression resistance from previously susceptible species resulting genetic mutations and/or subpopulations. Strategies for appropriate use need to be developed prevent further development resistance.