A prospective controlled investigation of prophylactic trimethoprim/sulfamethoxazole in hospitalized granulocytopenic patients

作者: Marc J. Gurwith , James L. Brunton , Beverley A. Lank , Godfrey K.M. Harding , Allan R. Ronald

DOI: 10.1016/0002-9343(79)90539-4

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摘要: Abstract Oral trimethoprim/sulfamethoxazole (TMP/SMZ) therapy was investigated in the prophylaxis of infections granulocytopenia. Hospitalized granulocytopenic patients were allocated at random to receive TMP/SMZ (group 1) or a control group 2). The percentage febrile days significantly reduced 1,19 per cent compared 39 2 (P

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