Hybrid imaging (SPECT/CT and PET/CT): improving therapeutic decisions.

摘要: The incremental diagnostic value of integrated positron emission tomography–computed tomography (PET/CT) or single-photon computed (SPECT)/CT images compared with PET SPECT alone, correlated a CT obtained at different time includes the following: (1) improvement in lesion detection on both and images, (2) localization foci uptake resulting better differentiation physiological from pathologic uptake, (3) precise malignant foci, for example, skeleton vs soft tissue liver adjacent bowel node (4) characterization serendipitous lesions, (5) confirmation small, subtle, unusual lesions. use these techniques can occur initial diagnosis, assessing early response disease to treatment, conclusion continuing follow-up patients. PET/CT SPECT/CT fusion affect clinical management significant proportion patients wide range diseases by guiding further procedures, excluding need changing inter- intramodality therapy, including soon after treatment has been initiated, providing prognostic information. have potential provide important information guide biopsy mass active regions tumor maps than alone modulate field dose radiation therapy. It is expected that role will continue evolve future tools be fundamental components truly "personalized medicine" we are striving deliver.