Posterior parietal cortex dynamically ranks topographic signals via cholinergic influence

摘要: The hypothesis to be discussed in this review is that posterior parietal cortex directly involved selecting relevant stimuli and filtering irrelevant distractors. receives input from several sensory modalities integrates them part direct the allocation of resources optimize gains. In conjunction with prefrontal cortex, nucleus accumbens, basal forebrain cholinergic nuclei, it comprises a network mediating sustained attentional performance. Numerous anatomical, neurophysiological, lesion studies have substantiated notion basic functions are conserved rodents humans. One such function detection selection necessary for making optimal choices or responses. issues addressed here how behaviorally targets recruit oscillatory potentials spiking activity neurons compared similar yet stimuli. Further, influence cortical learning decision-making also discussed. I propose these neurophysiological correlates attention transmitted frontal areas contributing top down timely manner.