Sensitivity analysis to derive a food consumption point estimate for deterministic food allergy risk assessment

摘要: One of the input parameters in food allergy risk assessment is amount a given consumed at an eating occasion. There no consensus on how to use consumption data when assessing from unintended allergen presence products. A sensitivity analysis was performed establish optimal estimate for deterministic assessment. Exposure calculated percentiles (50th percentile, P50 maximum) using iFAAM database conjunction with concentration range 1 1000 ppm. The resulting intakes were compared allergic population reference doses proposed by Taylor et al. (2014) 10 major allergenic foods. Optimal defined as those which predicted intake below relevant dose and met acceptable level confirmed probabilistic assessments. Analysis showed that, 99% groups, our criteria, while P75 did so 100% groups. We suggest that point It meets safety objective adequately conservative public health context.