Combinatorial vascular targeting in translational medicine
作者： Fernanda I. Staquicini , Benjamin J. Moeller , Wadih Arap , Renata Pasqualini
关键词:
摘要: In the post-genomic era, phage display technology surfaces as an alternative approach for large-scale study of tissue-specific protein interactions with direct clinical and therapeutic applications. The unbiased identification molecular complexes expressed on surface cells blood vessels organs tissues may eventually lead to a considerably improved understanding cellular vascular proteomics. ultimate value this consists in conception new ligand-directed pharmacology, broad implications both treatment imaging cancer patients. review, we describe use applications efficient development targeted drug discovery design.
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