Image-guided surgery in cancer: A strategy to reduce incidence of positive surgical margins.

摘要: Primary treatment for many solid cancers includes surgical excision or radiation therapy, with without the use of adjuvant therapy. This can include addition and chemotherapy after primary salvage surgery to Both therapies, radiation, require precise anatomic localization tumor. If tumor is not targeted adequately initial treatment, disease recurrence may ensue, if targeting too broad, unnecessary morbidity occur nearby structures remaining normal tissue. Fluorescence imaging using intraoperative contrast agents a rapidly growing field improving visualization in cancer facilitate resection order obtain negative margins. There are multiple strategies based on antibodies against surface markers ligands receptors preferentially expressed cancer. In this article, we review incidence clinical implications positive margins some most common tumors. Within context, present ongoing preclinical studies focused improve article categorized under: Laboratory Methods Technologies > Imaging.