Effect of intracerebroventricularly infused glucagon on feeding behavior.
作者： Akira Inokuchi , Yutaka Oomura , Hiroyuki Nishimura
DOI: 10.1016/0031-9384(84)90160-4
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摘要: Abstract Administration of pancreatic glucagon into 3rd cerebral ventricle rats suppressed feeding with potency greater than 1000 times that peripheral administration. A low dose (5 ng) food intake mainly in short-term and slightly long-term. medium (25 produced delayed suppression. high (100 only intake. From this evidence, it is conclued intracerebroventricular administration physiological concentration suppresses through the hypothalamus. The possible mechanism suppression by discussed.
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