Muscle Mass Index and Animal Source of Dietary Protein Are Positively Associated with Insulin Resistance in Participants of the NuAge Study.

摘要: Contribute evidence towards the complex interrelationships of body composition, insulin sensitivity and protein intake independently from adiposity in an older population. This is a cross-sectional analysis existing dataset which literature-supported model linking together variables interest tested using path analysis. The loss muscle mass has been implicated development resistance. We propose to test associations with their respective animal vegetable sources intake, adiposity. Non-diabetic participants aged 68–82 years NuAge study all available measures (n=441) were included. A considering age, sex, chronic diseases, physical activity; smoking influencing composition components was created Path Analysis for independent associations. Muscle index (MMI; kg/height m2) % fat derived DXA BIA. Insulin resistance estimated by Homeostatic Model Assessment Resistance (HOMA-IR) score activity Physical Activity Scale Elderly (PASE) questionnaire. Protein intakes obtained three non-consecutive 24h-diet recalls. In final model, direct positive observed between HOMA-IR MMI (β=0.42; 95%CI: 0.24; 0.6) (β=0.094; 0.07; 0.11). There no or HOMA-IR. significant negative association plant (β= -0.068; -0.13; -0.003) indirect mediated through (β=0.0321; 0.01; 0.05), as well -0.07; -0.1; 0.0). Our indicated that HOMA significantly positively associated. related differently fat, respectively.