Definitive abdominal wall closure using a porcine intestinal submucosa biodegradable membrane in pediatric transplantation

摘要: Abdominal closure in children less than 10 kg following liver or kidney transplantation can be challenging. Excessive pressure attained from a tight result abdominal compartment syndrome, graft compromise and loss. Concerns over using prosthetic patches are that of infection dehiscence. We report series definitive wall biodegradable membrane porcine intestinal submucosa (Surgisis � ; Cook Biotech Incorpo- rated, West Lafayette, IN, USA). A prospective collection follow up transplant patients weighing who required augmentation with Surgisisin order to achieve satisfactory closure. There were two renal trans- plant patients. The average weight the was 6.6 (5.4-8.5 kg) 9.8 kg. area Surgisis used 71.2 cm 2 (25-160 ) length 15.3 months (1-27 months). Concomitant measures aid included bilateral recipient nephrectomy for reduction by 33% lateral segmental grafts Delayed occurred all except one days first surgery 3.75 (0-6 days). Following patient died multiple organ failure at month secondary hemophagocytosis underlying combined immune deficiency syndrome pa- tient hepatic artery thrombosis salvaged re-exploration. wound complications, developed small sinuses some skin dehiscence which healed four second sinus trans-patch biopsy three wk. Both had positive microbial cultures but neither necessitated removal graft. no incisional hernias. Surgisisis safe method facilitating pediatric It appears have long-term durability hernias on short- medium-term up, is fairly resistant infection.