Influence of genetic discrimination perceptions and knowledge on cancer genetics referral practice among clinicians

摘要: Purpose: To describe nongenetics clinicians' perceptions and knowledge of cancer genetics laws prohibiting genetic discrimination, attitudes toward the use testing, referral practices. Methods: Invitations to participate were sent a random stratified sample California Medical Association members all Nurse Practitioners Latino Association. Responders in active practice eligible completed 47-item survey. Results: There 1181 qualified participants (62% physicians). Although 96% viewed testing as beneficial for their patients, 75% believed fear discrimination would cause patients decline testing. More than 60% not aware federal or health insurance discrimination—concern about was selected reason nonreferral by 11%. A positive attitude strongest predictor (odds ratio: 3.55 [95% confidence interval: 2.24-5.63], P < 0.001) stepwise logistic regression analyses. The higher belief less likely participant refer 0.72 0.518-0.991], 0.05), whereas more law associated with comfort recommending 1.18 1.11-1.25], actual 0.001). Conclusion: Concerns deficits may be barriers referrals. Clinician education help promote access screening prevention.