Gastric Cardia Carcinoma is Associated with the Promoter -77T>C Gene Polymorphism of X-Ray Cross-Complementing Group 1 (XRCC1)
作者： Giovanni Corso , Daniele Marrelli , Corrado Pedrazzani , José Carlos Machado , Stefano Mancini
DOI: 10.1007/S11605-009-0980-X
关键词:
摘要: Purpose X-ray repair cross complementing group 1 (XRCC1) is one of the major DNA proteins involved in bas-excision pathway. Several single-nucleotide polymorphisms XRCC1 gene are identified and related with increased cancer risk development. In particular, -77T>C polymorphism located on promoter region relates lung The aim this study to analyze allelic frequencies a population composed 456 primary gastric patients (GC) 507 blood donor controls.
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