Current medical treatment for tuberculosis

作者: E. D Chan

DOI: 10.1136/BMJ.325.7375.1282

关键词:

摘要: Instigating effective treatment regimens in a way that improves patient adherence is vital to tackling the global resurgence of tuberculosis About one third world's population has latent tuberculosis, caused by Mycobacterium infection.1 From this pool, roughly 9 million cases active emerge annually, resulting 2-3 deaths. Most new occur most populated nations—India and China—but highest rates disease are seen sub-Saharan Africa, Indonesian Philippine archipelagos, Afghanistan, Bolivia, Peru. In these regions case typically exceed 300 per 100 000 year. 1 2 Although incidence declined North America western Europe throughout latter half 20th century, have increased over past 10 years mainly because immigration, HIV/AIDS, neglect control programmes. 3 4 One factor curbing increase instigation proper not only encompasses an regimen but also ensures compliance with response treatment. This review highlights current recommendations for tuberculosis. #### Summary points Many people worldwide or number expected future The common cause failure acquired drug resistance non-adherence; predicting non-adherence highly problematic Directly observed therapy means combatting intermittent (less than daily) facilitate therapy Testing susceptibility drugs essential identifying tailoring treatment Managing multidrug resistant complex should, when possible, be done specialised programmes We performed Medline search using key words “tuberculosis therapy” find pertinent literature. We searched bibliographies …

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