Collagen and chondrocyte concentrations control ultrasound scattering in agarose scaffolds
作者： S. Inkinen , J. Liukkonen , J.H. Ylärinne , P.H. Puhakka , M.J. Lammi
DOI: 10.1016/J.ULTRASMEDBIO.2014.03.016
关键词:
摘要: Ultrasound imaging has been proposed for diagnostics of osteoarthritis and cartilage injuries in vivo. However, the specific contribution chondrocytes collagen to ultrasound scattering articular not systematically studied. We investigated role these tissue structures by measuring agarose scaffolds with varying chondrocyte concentrations. catheters center frequencies 9 MHz (7.1-11.0 MHz, -6 dB) 40 (30.1-45.3 were applied using an intravascular device. backscattering quantified a region interest starting right below sample surface differed significantly (p < 0.05) concentrations chondrocytes. An frequency as compared was more sensitive variations The present findings may improve diagnostic interpretation arthroscopic provide information necessary development models describing propagation within cartilage.
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