Second neoplasm after treatment of localized prostate cancer
作者： E. Arias , P. Astudillo , C. Manterola
DOI: 10.1016/J.ACUROE.2011.10.008
关键词:
摘要: Abstract Introduction Prostate cancer (PC) treatment in early stages is radical prostatectomy (RP) or external radiotherapy (ER). There some uncertainty regarding the development of new ER induced malignant tumors second primary tumor (SPT), a fact influencing choice therapy. The purpose this study to determine best therapeutic alternative for localized PC, regards incidence and time development. Material methods A systematic review literature proposed by means evaluation studies conducted with PC treated RP ER, published between 1990 2010. Mega searchers used were Cochrane Library Trip Database, databases MEDLINE, OVID, Science Direct, SciELO LiLACS, using MeSH terms free words. selected analyzed MINCIR score methodological quality (MQ) compare articles different design. variables considered be number patients treated, localization lesions, global STP MQ studies. Averages, medians weighted averages (WA) calculated. groups compared 95% confidence intervals medians. Results Eleven fulfilled screening criteria (retrospective cohorts case series); providing 13 series study. average was 14.7 points (13 16 points). most frequent localizations bladder, rectum long. WA 3.6% (4.1% 2.2% RP). Conclusion information existing did not make it possible demonstrate an association appearance therapies even though there superior tendency irradiated patients.
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