Precise Control of Cell Adhesion by Combination of Surface Chemistry and Soft Lithography

摘要: The adhesion of cells on an extracellular matrix (ECM) (in vivo) or the surfaces materials vitro) is a prerequisite for most to survive. rapid growth nano/microfabrication and biomaterial technologies has provided new with excellent specific, desirable biological interactions their surroundings. On one hand, chemical physical properties material exert extensive influence cell adhesion, proliferation, migration, differentiation. other are useful fundamental biology research tissue engineering. In this Review, overview will be given newly developed effects, as well soft lithographic techniques applications in research. Recent advances manipulation by combination surface chemistry lithography also highlighted.