Pharmacogenomics in the Evaluation of Efficacy and Adverse Events During Clinical Development of Vaccines

作者: Lennart J. Nilsson , Karin J. Regnström

DOI: 10.1007/978-1-59745-205-2_17

关键词:

摘要: The understanding of vaccine-induced immune responses in adults and infants is limited. Current vaccination schedules for are frequently debated. Especially, the relationship among timing, frequency dosing, generation an immunological memory Vaccine antigen-induced cytokine to vaccinations given infancy particular interest because little known about cellular this age, information available based on antibody responses. Pharmacogenomics ideally suited study related response, addition, toxicity, inflammation, apoptosis, stress, oncogenesis can be monitored, since expression thousands genes measured a single experiment. © 2008 Humana Press, part Springer Science + Business Media, LLC.

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