The morphology and function of healing cat corneal endothelium.

摘要: We mechanically damaged the entire corneal endothelium of one eye each ten cats and then examined both eyes by fluorophotometry specular microscopy for 5 months. Six weeks after damage, when corneas had cleared sufficiently to make accurate measurements, mean endothelial permeability carboxyfluorescein was increased 11% (P = 0.02) central thickness 0.05) in eyes. The pump rate decreased 29% 0.05), indicating that increase insufficient explain thickness. returned normal 3 months cell size 89% less than 0.01), coefficient variation 200% percentage hexagonal cells 34% 0.01). By months, changed very little, none three morphologic measurements normal. As rabbits, barrier recovers before wounding. Unlike functional recovery requires at least several Such prolonged trauma might also be expected humans who, like unlike have little capacity mitosis during healing.