Eicosapolyenoic acids of serum lipids of japanese islanders with low incidence of cardiovascular diseases

摘要: Japanese are unique among the peoples of developed countries in having a high intake eicosapentaenoic acid (C 20:5) from fresh fish and this may part contribute to their low incidence cardiovascular diseases. Mass spectroscopic analyses eicosapolyenoic acids (C20:3, C20:4 C20:5) were carried out on serum aged persons living Kohama island Okinawa known have lowest diseases Japan. All but 4 77 examined (73.94 +/- 7.81 years old) led active fishing-farming lives. The total amount (46.77 7.46 mg/100 ml) was higher (p less than 0.001) that people mainland Japan, owing (147.7 g/day). A positive correlation 0.01) found between C 20:5 concentration (6.82 2.54 density lipoprotein (55.38 13.83 ml). In addition, there correlations 20:3 (6.58 1.61 cholesterol (188.60 32.30 ml), triglyceride skinfold thickness. blood pressure level 0.01), abnormal ECG 0.05), salt (6.2-8.3 g/day) estimated urinalysis, all lower average figures for similar ages. No showed Q-wave ECG. percentage smokers drinkers