ESM-1 regulates cell growth and metastatic process through activation of NF-κB in colorectal cancer.
作者： Yun Hee Kang , Na Young Ji , Seung Ro Han , Chung Il Lee , Jae Wha Kim
DOI: 10.1016/J.CELLSIG.2012.06.004
关键词:
摘要: In our previous study, we reported that endothelial cell specific molecule-1 (ESM-1) was increased in tissue and serum from colorectal cancer patients and suggested that ESM-1 can be used as a potential serum marker for early detection of colorectal cancer. The aim of this study was to evaluate the role of ESM-1 as an intracellular molecule in colorectal cancer. ESM-1 expression was knocked down by small interfering RNA (siRNA) in colorectal cancer cells. Expression of ESM-1 siRNA decreased cell survival through the Akt-dependent …
kribb.re.kr参考文章(38)
Bharat B. Aggarwal, Nuclear factor-κB: The enemy within Cancer Cell. ,vol. 6, pp. 203- 208 ,(2004) , 10.1016/J.CCR.2004.09.003
Zou Ai-ping, Cheng Gang, Pi Ye-qin, Wang Wei-han, Yu Shang-bin, Wang Di-xun, The role of lipoxygenase and cyclooxygenase metabolites in acute hypoxic pulmonary vasoconstriction in piglets Journal of Tongji Medical University. ,vol. 9, pp. 239- 243 ,(1989) , 10.1007/BF02909091
C. Bubici, S. Papa, C.G. Pham, Guido Franzoso, F. Zazzeroni, The NF-kappaB-mediated control of ROS and JNK signaling. Histology and Histopathology. ,vol. 21, pp. 69- 80 ,(2006) , 10.14670/HH-21.69
Alfonso Bellacosa, C. Chandra Kumar, Antonio Di Cristofano, Joseph Robert Testa, Activation of AKT kinases in cancer: implications for therapeutic targeting. Advances in Cancer Research. ,vol. 94, pp. 29- 86 ,(2005) , 10.1016/S0065-230X(05)94002-5
Noor EMBI, Dennis B. RYLATT, Philip COHEN, Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle FEBS Journal. ,vol. 107, pp. 519- 527 ,(2005) , 10.1111/J.1432-1033.1980.TB06059.X
Tong Sun, Marbelys Rodriguez, Leung Kim, Glycogen synthase kinase 3 in the world of cell migration. Development Growth & Differentiation. ,vol. 51, pp. 735- 742 ,(2009) , 10.1111/J.1440-169X.2009.01141.X
David Béchard, Thibaut Gentina, Maryse Delehedde, Arnaud Scherpereel, Malcolm Lyon, Marc Aumercier, Rosemay Vazeux, Colette Richet, Pierre Degand, Brigitte Jude, Anne Janin, David G. Fernig, André-Bernard Tonnel, Philippe Lassalle, Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity Journal of Biological Chemistry. ,vol. 276, pp. 48341- 48349 ,(2001) , 10.1074/JBC.M108395200
D S Bassères, A S Baldwin, Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene. ,vol. 25, pp. 6817- 6830 ,(2006) , 10.1038/SJ.ONC.1209942
Noan-Minh Chau, Margaret Ashcroft, Akt2: a role in breast cancer metastasis Breast Cancer Research. ,vol. 6, pp. 55- 57 ,(2003) , 10.1186/BCR739
A. van de Stolpe, E. Caldenhoven, B.G. Stade, L. Koenderman, J.A. Raaijmakers, J.P. Johnson, P.T. van der Saag, 12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter. Journal of Biological Chemistry. ,vol. 269, pp. 6185- 6192 ,(1994) , 10.1016/S0021-9258(17)37586-5