作者: David Langenberger , Sebastian Bartschat , Jana Hertel , Steve Hoffmann , Hakim Tafer
DOI: 10.1007/978-3-642-22825-4_1
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摘要: The avalanche of next generation sequencing data has led to a rapid increase annotated microRNAs in the last few years. Many them are specific individual species or rather narrow clades. A closer inspection current version miRBase shows that dozens entries conflict with other ncRNAs, particular snoRNAs.With exceptions, these cases show little similarities canonical microRNAs, however, and thus they should be considered as mis-annotations.