Superabsorbent polymer-containing wound dressings have a beneficial effect on wound healing by reducing PMN elastase concentration and inhibiting microbial growth
作者： C. Wiegand , M. Abel , P. Ruth , U. C. Hipler
DOI: 10.1007/S10856-011-4423-3
关键词:
摘要: A comprehensive in vitro approach was used to assess the effects of superabsorbent polymer (SAP) containing wound dressings treatment non-healing wounds. slight negative effect on HaCaT cells noted which is most likely due Ca2+ deprivation medium by binding SAP. It could be shown that SAP are able bind considerable amounts elastase reducing enzyme activity significantly. Furthermore, SAP’s inhibit formation free radicals. The SAP-containing tested also exhibited a significant strong antimicrobial effectively impeding growth gram-negative and gram-positive bacteria as well yeasts. In conclusion, data confirm positive observed vivo suggest they should specifically useful for cleansing.
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