Temperature-Dependent Properties of Cells Transformed by a Thermosensitive Mutant of Polyoma Virus
作者： R. Dulbecco , W. Eckhart
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摘要: In cells transformed by ts-3, a thermosensitive mutant of polyoma virus, the loss inhibition DNA synthesis topographical factors (topo-inhibition), is rendered temperature-dependent, providing evidence that viral genome controls this essential aspect transformation. The expression two other attributes cells, growth in agar and serum requirement for initiation wound culture, not made temperature-dependent. productive infection BALB-3T3 virus-induced stimulation cellular movement
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