Mutation profiling in tumor samples using the Sequenom OncoCarta|[trade]| Panel
作者： Marisa Pearce , Amy Cullinan , Grant Hogg , Dana Hosseini , Mathias Ehrich
DOI: 10.1038/NMETH.F.254
关键词:
摘要: Sequenom's MassARRAY® system enables sensitive and rapid somatic mutation profiling in solid tumors or cell lines. Our validation studies revealed mutations most of the oncogenes analyzed, frequency was consistent with previous reports. We also found new low-frequency our tumor samples, indicating that rare potentially targetable can be identified this approach.
nature.com
sci-hub.se 参考文章(4)
Stephen J Chanock, Gilles Thomas, The devil is in the DNA. Nature Genetics. ,vol. 39, pp. 283- 284 ,(2007) , 10.1038/NG0307-283
Christian Jurinke, Paul Oeth, Dirk van den Boom, MALDI-TOF mass spectrometry: a versatile tool for high-performance DNA analysis. Molecular Biotechnology. ,vol. 26, pp. 147- 163 ,(2004) , 10.1385/MB:26:2:147
A Vivante, N Amariglio, M Koren-Michowitz, O Ashur-Fabian, A Nagler, G Rechavi, Y Cohen, High-throughput, sensitive and quantitative assay for the detection of BCR-ABL kinase domain mutations Leukemia. ,vol. 21, pp. 1318- 1321 ,(2007) , 10.1038/SJ.LEU.2404635
Scott A Armstrong, Ingo K Mellinghoff, F Stephen Hodi, Glenn Dranoff, Paul S Mischel, Tim F Cloughesy, Stan F Nelson, Linda M Liau, Kirsten Mertz, Mark A Rubin, Holger Moch, Massimo Loda, William Catalona, Jonathan Fletcher, Sabina Signoretti, Frederic Kaye, Kenneth C Anderson, George D Demetri, Reinhard Dummer, Stephan Wagner, Meenhard Herlyn, William R Sellers, Matthew Meyerson, Levi A Garraway, Roman K Thomas, Alissa C Baker, Ralph M DeBiasi, Wendy Winckler, Thomas LaFramboise, William M Lin, Meng Wang, Whei Feng, Thomas Zander, Laura E MacConaill, Jeffrey C Lee, Rick Nicoletti, Charlie Hatton, Mary Goyette, Luc Girard, Kuntal Majmudar, Liuda Ziaugra, Kwok-Kin Wong, Stacey Gabriel, Rameen Beroukhim, Michael Peyton, Jordi Barretina, Amit Dutt, Caroline Emery, Heidi Greulich, Kinjal Shah, Hidefumi Sasaki, Adi Gazdar, John Minna, High-throughput oncogene mutation profiling in human cancer Nature Genetics. ,vol. 39, pp. 347- 351 ,(2007) , 10.1038/NG1975