Balancing the innate immune system in tumor development
作者： Catharina Hagerling , Amy-Jo Casbon , Zena Werb
DOI: 10.1016/J.TCB.2014.11.001
关键词:
摘要: Cells of the innate immune system have a dual role in cancer development both tumor initiation and progression. Innate cells can, on one hand, aid malignant transformation outgrowth and, other prevent The has ability to tune inflammatory response is key player cancer-related inflammation, which can precede malignancy or be induced by oncogenic changes promoting protumor milieu. In this review, we discuss emerging cellular molecular mechanisms inflammation progression, point outstanding questions that remain.
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