Sentinel node mapping affects intraoperative pulse oximetric recordings during breast cancer surgery

摘要: Background:  In invasive breast cancer lymphatic mapping with patent blue vital dye (PBV) is used intraoperatively to identify the sentinel lymph nodes: first axillary node draining mammary basin and involved by metastatic growth in cancer. Patent spreads tissues giving a bluish tinge patients. We have noted possibility that intraoperative peripheral pulse oximetric (SpO2) values are artificially low when intradermal PBV used. Methods:  Twenty patients normal pulmonary function undergoing surgery standardized anesthesia either did or not receive marking. The radial artery was cannulated for blood-gas-analysis; arterial oxygen tension (PaO2); saturation (SaO2). Peripheral measured using light absorption technique. Red infrared (660 900 nm), pulseoxymetry, partially absorbed passing through tissue. amount of sensored calculated. color skin evaluated. Results:  decreased only immediately after injection PBV, remained at significantly lower level (P<0.001) throughout operation up 90 min postoperatively. Arterial SaO2 decrease PBV. made patients' more (P<0.001). No changes SpO2, PaO2 were found control patients. Conclusion:  spectrum has peak 640 nm, thus making SpO2 incorrect. falsely true oxygenation impaired during mapping.