A comparison of two rapid whole-blood tests and laboratory serology, in the diagnosis of Helicobacter pylori infection.

摘要: Objective To compare two rapid whole-blood serology tests for Helicobacter pylor. and a laboratory assay against gold standard. Design Prospective comparison of in 81 patients. Setting A hospital access endoscopy clinic. Participants Dyspeptic patients requiring assessment H. pylori status. Interventions Measurement antibody status by Quickvue One-step, Helisal, Premier test; 13 C urea breath test pylori, gastric biopsies histology, culture urease Main outcome measure Sensitivity specificity Helisal tests, compared to standard based on test, biopsy culture, histology Results The has significantly greater sensitivity (81%) than (67%), but without appreciable loss (86% 93%, respectively). is more sensitive both the blood (96%), with comparable assay. Conclusion used this study are quick convenient use, do not approach detecting group dyspeptic attending an