Surveillance of primitive cells by natural killer cells.

摘要: Natural killer cells (NK cells) were originally described and defined as a distinct group of using in vitro cytolytic assays against malignant (Kiessling et al. 1975a; Herberman 1975b). The fact that the NK constitute such recent discovery may part be due to previous prevailing focus tumor immunology requiring strict specificity an immune reaction allow proper interest It is now clear are able endow individual with capacity, is, exclude occurrence certain diseases. However, it equally patterns expressed by “broader” type than displayed T or B lymphocytes conventional antigens. Still, little doubt exists do indeed express selectivity their lytic binding 1975). specific profile lysis one best accepted markers for cells, since natural have very few on surface which define cell being studied Wigzell 1979).