Immunotherapies for neurodegenerative diseases: current status and potential of plant-made biopharmaceuticals.

作者: Jaime I Arevalo-Villalobos , Sergio Rosales-Mendoza , Sergio Zarazua

DOI: 10.1080/14760584.2016.1229602

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摘要: ABSTRACTIntroduction: Neurodegenerative diseases (NDs) have a serious impact on global health with no effective treatments available to date. Vaccination has been proposed as therapeutic approach for NDs, and clinical evaluations of some candidates Alzheimer’s disease multiple sclerosis are ongoing. Moreover, monoclonal antibodies passive immunotherapy under evaluation Alzheimer’s, synucleinopathies, sclerosis.Areas covered: With the consolidation plant-based systems production oral delivery biopharmaceuticals, interesting perspectives arise in fight against NDs. Based analysis current biomedical literature, role plant-made biopharmaceuticals outlook how this technology is leading new potential developments NDs presented review.Expert commentary: Substantial innovations following years expected consequence applying molecular pharming

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