Cyclin H expression is increased in GIST with very-high risk of malignancy
作者： Julian Dorn , Hanno Spatz , Michael Schmieder , Thomas FE Barth , Annette Blatz
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摘要: Background Risk estimation of gastrointestinal stromal tumours (GIST) is based on tumour size and mitotic rate according to the National Institutes Health consensus classification. The indication for adjuvant treatment patients with high risk GIST after R0 resection small molecule inhibitors still a controversial issue, since these represent highly heterogeneous population. Therefore, additional prognostic indicators are needed. Here, we evaluated value cyclin H expression in GIST.
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